In rare cases, nausea and vomiting can become so severe that the mother has to be hospitalized. This condition, called hyperemesis gravidarum, recently afflicted the Duchess of Cambridge Kate Middleton, and might have contributed to the death of English novelist Charlotte Bronte. Diclegis was tested in a trial of 261 pregnant women experiencing nausea. After two weeks, the women taking the drug saw a greater improvement in their symptoms than the group taking placebo.
The drug is taken daily, on an empty stomach and usually at bedtime. The most common side effect is drowsiness, so expectant moms should avoid taking it right before driving or taking their bulldozer out for a spin. A previous formulation called Bendectin, was approved by the FDA in 1956. Though Merrell Dow maintained that the drug was never proved hazardous, and the FDA never recalled it, a wave of bad press and mounting litigation and insurance costs prompted the drug maker to pull Bendectin off the shelf in 1983. There were some studies that established a link between the drug and birth defects that asked mothers of malformed and normal children about their pregnancies, but these may have fallen prey to unconscious biases.
Parties have claimed that the drug caused damage in just about every system of the body, from respiratory defects to musculoskelatory problems to cancer. One of the expert witnesses in several lawsuits against Merrell Dow was Australian doctor William McBride, who first brought to light the birth defects associated with the anti-nausea drug thalidomide, and published a paper linking Bendectin referred to by its The doctor had added fictitious animals and changed the dosages used.
Editions Nov 23, 3:28 PM EST SubscribeEverything You Need To Know, Right Now. Everything You Need To Know, Right Now. Please enter a valid paper essay helper Search Search googletag. There was also never very much clarity about how exactly Bendectin was supposed to have damaged fetuses. The IBTech Newsletter keeps you connected to the biggest stories unfolding in technology. Please enter a valid email googletag. Technology The National Highway Traffic Safety Administration has created guidelines for phone manufacturers to create a 'driver mode' that would limit access to certain apps while behind the wheel.
World The country is lacking both basic and life-saving medicine in the wake of its currency floatation. National Black Friday will have plenty of good deals for those looking to increase their digital storage options. IBTAbout UsAdvertise with UsMedia KitTerms of Paper essay helper PolicyEditionsAustraliaChinaIndiaItalyJapanSingaporeUnited KingdomUnited States. Unfortunately, the royal family was forced to announce the pregnancy early, thanks to a rare but severe form of morning sickness.
The duchess is suffering from hyperemesis gravidarum HG -again. She suffered from this during her first pregnancy, too. The condition is diagnosed when a pregnant woman loses more than 10 pounds due to extreme and persistent nausea and vomiting, according to the Cleveland Clinic. The duchess is not yet 12 weeks into her second pregnancy, royal officials told ABC News, and doctors are treating her at Kensington Palace. They said she "may require supplementary hydration, medication and nutrients.
Treatment often begins with dietary changes and the consumption of small, protein-filled snacks, rather than large meals. If weight loss continues, and the woman is hospitalized, treatments can include pyridoxine, a high-dose vitamin B6, and doxylamine, an antihistamine, the combination of which can ease nausea, Dr. Irina Burd, director of research for the division of maternal fetal medicine at Johns Hopkins University in Maryland, told Yahoo Health. Symptoms of HG most often spike between the 10th and 12th weeks of pregnancy, often subsiding between week 14 and 16.
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